| 1959 Purdue Football Schedule | | | | |
| 18-Sep | at | UCLA | T | 0 | 0 | |
| 3-Oct | | Notre Dame | W | 28 | 7 | |
| 10-Oct | | Wisconsin | W | 21 | 0 | |
| 17-Oct | at | Ohio State | L | 0 | 15 | |
| 24-Oct | | Iowa | W | 14 | 7 | |
| 31-Oct | at | Illinois | T | 7 | 7 | |
| 7-Nov | at | Michigan State | L | 0 | 15 | |
| 14-Nov | | Minnesota | W | 29 | 23 | |
| 21-Nov | at | Indiana | W | 10 | 7 | |
| | 5-2-2 | | 109 | 81 | |
| | | | | | |
| 1958 Purdue Football Schedule | | | | |
| 27-Sep | | Nebraska | W | 28 | 0 | |
| 4-Oct | at | Rice | W | 24 | 0 | |
| 11-Oct | at | Wisconsin | L | 6 | 31 | |
| 18-Oct | | Michigan State | W | 14 | 6 | |
| 25-Oct | at | Notre Dame | W | 29 | 22 | |
| 1-Nov | | Illinois | W | 31 | 8 | |
| 8-Nov | at | Ohio State | T | 14 | 14 | |
| 15-Nov | at | Northwestern | W | 23 | 6 | |
| 22-Nov | | Indiana | T | 15 | 15 | |
| | 6-1-2 | | 184 | 102 | |
| | | | | | |
| 1957 Purdue Football Schedule | | | | |
| 28-Sep | | Notre Dame | L | 0 | 12 | |
| 5-Oct | at | Minnesota | L | 17 | 21 | |
| 12-Oct | | Wisconsin | L | 14 | 23 | |
| 19-Oct | at | Michigan State | W | 20 | 13 | |
| 26-Oct | | Miami | W | 37 | 6 | |
| 2-Nov | at | Illinois | W | 21 | 6 | |
| 9-Nov | at | Ohio State | L | 7 | 20 | |
| 16-Nov | | Northwestern | W | 27 | 0 | |
| 23-Nov | at | Indiana | W | 35 | 13 | |
| | 5-4-0 | | 178 | 114 | |
| | | | | | |
| 1956 Purdue Football Schedule | | | | |
| 29-Sep | | Missouri | W | 16 | 7 | |
| 6-Oct | at | Minnesota | L | 14 | 21 | |
| 13-Oct | at | Notre Dame | W | 28 | 14 | |
| 20-Oct | at | Wisconsin | T | 6 | 6 | |
| 27-Oct | | Iowa | L | 20 | 21 | |
| 3-Nov | | Illinois | T | 7 | 7 | |
| 10-Nov | at | Michigan State | L | 9 | 12 | |
| 17-Nov | at | Northwestern | L | 0 | 14 | |
| 24-Nov | | Indiana | W | 39 | 20 | |
| | 3-4-2 | | 139 | 122 | |
| | | | | | |
| 1955 Purdue Football Schedule | | | | |
| 24-Sep | | Pacific | W | 14 | 7 | |
| 1-Oct | at | Minnesota | W | 7 | 6 | |
| 8-Oct | | Wisconsin | L | 0 | 9 | |
| 15-Oct | at | Iowa | T | 20 | 20 | |
| 22-Oct | | Notre Dame | L | 7 | 22 | |
| 29-Oct | at | Illinois | W | 13 | 0 | |
| 5-Nov | | Michigan State | L | 0 | 27 | |
| 12-Nov | | Northwestern | W | 46 | 8 | |
| 19-Nov | at | Indiana | W | 6 | 4 | |
| | 5-3-1 | | 113 | 103 | |
| | | | | | |
| 1954 Purdue Football Schedule | | | | |
| 25-Sep | | Missouri | W | 31 | 0 | |
| 2-Oct | at | Notre Dame | W | 27 | 14 | |
| 9-Oct | | Duke | T | 13 | 13 | |
| 16-Oct | at | Wisconsin | L | 6 | 20 | |
| 23-Oct | at | Michigan State | W | 27 | 13 | |
| 30-Oct | | Illinois | W | 28 | 14 | |
| 6-Nov | at | Iowa | L | 14 | 25 | |
| 13-Nov | | Ohio State | L | 6 | 28 | |
| 20-Nov | | Indiana | W | 13 | 7 | |
| | 5-3-1 | | 165 | 134 | |
| | | | | | |
| 1953 Purdue Football Schedule | | | | |
| 26-Sep | at | Missouri | L | 7 | 14 | |
| 3-Oct | | Notre Dame | L | 7 | 37 | |
| 10-Oct | at | Duke | L | 14 | 20 | |
| 17-Oct | | Wisconsin | L | 19 | 28 | |
| 24-Oct | | Michigan State | W | 6 | 0 | |
| 31-Oct | at | Illinois | L | 0 | 21 | |
| 7-Nov | | Iowa | L | 0 | 26 | |
| 14-Nov | at | Ohio State | L | 6 | 21 | |
| 21-Nov | at | Indiana | W | 30 | 0 | |
| | 2-7-0 | | 89 | 167 | |
| | | | | | |
| 1952 Purdue Football Schedule | | | | |
| 27-Sep | at | Penn State | T | 20 | 20 | |
| 4-Oct | at | Ohio State | W | 21 | 14 | |
| 11-Oct | | Iowa | W | 41 | 14 | |
| 18-Oct | | Notre Dame | L | 14 | 26 | |
| 25-Oct | at | Illinois | W | 40 | 12 | |
| 1-Nov | | Michigan State | L | 7 | 14 | |
| 8-Nov | at | Minnesota | T | 14 | 14 | |
| 15-Nov | at | Michigan | L | 10 | 21 | |
| 22-Nov | | Indiana | W | 21 | 16 | |
| | 4-3-2 | | 188 | 151 | |
| | | | | | |
| 1951 Purdue Football Schedule | | | | |
| 29-Sep | | Texas | L | 0 | 14 | |
| 6-Oct | | Iowa | W | 34 | 30 | |
| 12-Oct | at | Miami | L | 0 | 7 | |
| 20-Oct | | Wisconsin | L | 7 | 31 | |
| 27-Oct | at | Notre Dame | L | 9 | 30 | |
| 3-Nov | | Penn State | W | 28 | 0 | |
| 10-Nov | at | Northwestern | W | 35 | 14 | |
| 17-Nov | | Minnesota | W | 19 | 13 | |
| 24-Nov | at | Indiana | W | 21 | 13 | |
| | 5-4-0 | | 153 | 152 | |
| | | | | | |
| 1950 Purdue Football Schedule | | | | |
| 30-Sep | at | Texas | L | 26 | 34 | |
| 7-Oct | at | Notre Dame | W | 28 | 14 | |
| 14-Oct | | Miami | L | 14 | 20 | |
| 21-Oct | at | Iowa | L | 21 | 33 | |
| 28-Oct | | UCLA | L | 6 | 20 | |
| 4-Nov | at | Wisconsin | L | 7 | 33 | |
| 11-Nov | | Northwestern | L | 14 | 19 | |
| 18-Nov | at | Minnesota | L | 14 | 27 | |
| 25-Nov | | Indiana | W | 13 | 0 | |
| | 2-7-0 | | 143 | 200 | |
| | | | | | |
