| 1949 Purdue Football Schedule | | | | |
| 24-Sep | at | Northwestern | L | 6 | 20 | |
| 1-Oct | | Iowa | L | 7 | 21 | |
| 8-Oct | | Notre Dame | L | 12 | 35 | |
| 14-Oct | at | Miami | W | 14 | 0 | |
| 22-Oct | | Illinois | L | 0 | 19 | |
| 29-Oct | at | Minnesota | W | 13 | 7 | |
| 5-Nov | at | Michigan | L | 12 | 20 | |
| 12-Nov | | Marquette | W | 41 | 7 | |
| 19-Nov | at | Indiana | W | 14 | 6 | |
| | 4-5-0 | | 119 | 135 | |
| | | | | | |
| 1948 Purdue Football Schedule | | | | |
| 25-Sep | at | Notre Dame | L | 27 | 28 | |
| 2-Oct | at | Northwestern | L | 0 | 21 | |
| 9-Oct | | Michigan | L | 0 | 40 | |
| 16-Oct | at | Iowa | W | 20 | 13 | |
| 23-Oct | at | Illinois | L | 6 | 10 | |
| 30-Oct | | Marquette | W | 14 | 9 | |
| 6-Nov | at | Minnesota | L | 7 | 34 | |
| 13-Nov | | Pittsburgh | L | 13 | 20 | |
| 20-Nov | | Indiana | W | 39 | 0 | |
| | 3-6-0 | | 126 | 175 | |
| | | | | | |
| 1947 Purdue Football Schedule | | | | |
| 27-Sep | at | Wisconsin | L | 14 | 32 | |
| 4-Oct | | Ohio State | W | 24 | 20 | |
| 11-Oct | | Notre Dame | L | 7 | 22 | |
| 18-Oct | N | Boston University | W | 62 | 7 | Boston, MA |
| 25-Oct | | Illinois | W | 14 | 7 | |
| 1-Nov | | Iowa | W | 21 | 0 | |
| 8-Nov | at | Minnesota | L | 21 | 26 | |
| 15-Nov | | Pittsburgh | W | 28 | 0 | |
| 22-Nov | at | Indiana | L | 14 | 16 | |
| | 5-4-0 | | 205 | 130 | |
| | | | | | |
| 1946 Purdue Football Schedule | | | | |
| 21-Sep | | Miami | W | 13 | 7 | |
| 28-Sep | at | Iowa | L | 0 | 16 | |
| 5-Oct | at | Illinois | L | 7 | 43 | |
| 12-Oct | at | Notre Dame | L | 6 | 49 | |
| 19-Oct | at | Ohio State | T | 14 | 14 | |
| 26-Oct | at | Pittsburgh | W | 10 | 8 | |
| 2-Nov | | Wisconsin | L | 20 | 24 | |
| 9-Nov | at | Minnesota | L | 7 | 13 | |
| 23-Nov | | Indiana | L | 20 | 34 | |
| | 2-6-1 | | 97 | 208 | |
| | | | | | |
| 1945 Purdue Football Schedule | | | | |
| 22-Sep | | Marquette | W | 14 | 13 | |
| 29-Sep | at | Great Lakes Navy | W | 20 | 6 | |
| 6-Oct | at | Wisconsin | W | 13 | 7 | |
| 13-Oct | | Iowa | W | 40 | 0 | |
| 20-Oct | at | Ohio State | W | 35 | 13 | |
| 27-Oct | at | Northwestern | L | 14 | 26 | |
| 3-Nov | | Pittsburgh | W | 28 | 0 | |
| 10-Nov | | Miami | W | 21 | 7 | |
| 17-Nov | at | Michigan | L | 13 | 27 | |
| 24-Nov | at | Indiana | L | 0 | 26 | |
| | 7-3-0 | | 198 | 125 | |
| | | | | | |
| 1944 Purdue Football Schedule | | | | |
| 23-Sep | at | Great Lakes Navy | L | 18 | 27 | |
| 30-Sep | | Marquette | W | 40 | 7 | |
| 7-Oct | at | Illinois | W | 35 | 19 | |
| 14-Oct | | Iowa Pre-Flight | L | 6 | 13 | |
| 21-Oct | at | Iowa | W | 26 | 7 | |
| 28-Oct | at | Michigan | L | 14 | 40 | |
| 4-Nov | | Wisconsin | W | 35 | 0 | |
| 11-Nov | at | Northwestern | W | 27 | 7 | |
| 18-Nov | N | Navy | L | 0 | 32 | Baltimore, MD |
| 25-Nov | | Indiana | L | 6 | 14 | |
| | 5-5-0 | | 207 | 166 | |
| | | | | | |
| 1943 Purdue Football Schedule | | | | |
| 18-Sep | at | Great Lakes Navy | W | 23 | 13 | |
| 25-Sep | at | Marquette | W | 21 | 0 | |
| 2-Oct | | Illinois | W | 40 | 21 | |
| 9-Oct | | Camp Grant | W | 19 | 0 | |
| 16-Oct | N | Ohio State | W | 30 | 7 | Cleveland, OH |
| 23-Oct | | Iowa | W | 28 | 7 | |
| 30-Oct | at | Wisconsin | W | 32 | 0 | |
| 6-Nov | at | Minnesota | W | 14 | 7 | |
| 20-Nov | at | Indiana | W | 7 | 0 | |
| | 9-0-0 | | 214 | 55 | |
| | | | | | |
| 1942 Purdue Football Schedule | | | | |
| 26-Sep | | Fordham | L | 7 | 14 | |
| 3-Oct | at | Vanderbilt | L | 0 | 26 | |
| 10-Oct | at | Northwestern | W | 7 | 6 | |
| 17-Oct | at | Ohio State | L | 0 | 26 | |
| 24-Oct | | Wisconsin | L | 0 | 13 | |
| 31-Oct | at | Iowa | L | 7 | 13 | |
| 7-Nov | | Great Lakes Navy | L | 0 | 42 | |
| 14-Nov | at | Michigan State | L | 6 | 19 | |
| 21-Nov | | Indiana | L | 0 | 20 | |
| | 1-8-0 | | 27 | 179 | |
| | | | | | |
| 1941 Purdue Football Schedule | | | | |
| 27-Sep | | Vanderbilt | L | 0 | 3 | |
| 4-Oct | at | Pittsburgh | W | 6 | 0 | |
| 18-Oct | at | Ohio State | L | 14 | 16 | |
| 25-Oct | | Iowa | W | 7 | 6 | |
| 1-Nov | N | Fordham | L | 0 | 17 | New York, NY |
| 8-Nov | | Michigan State | T | 0 | 0 | |
| 15-Nov | at | Wisconsin | L | 0 | 13 | |
| 22-Nov | at | Indiana | L | 0 | 7 | |
| | 2-5-1 | | 27 | 62 | |
| | | | | | |
| 1940 Purdue Football Schedule | | | | |
| 28-Sep | | Butler | W | 28 | 0 | |
| 5-Oct | at | Ohio State | L | 14 | 17 | |
| 12-Oct | at | Michigan State | L | 7 | 20 | |
| 26-Oct | | Wisconsin | L | 13 | 14 | |
| 2-Nov | at | Iowa | W | 21 | 6 | |
| 9-Nov | N | Fordham | L | 7 | 13 | New York, NY |
| 16-Nov | at | Minnesota | L | 6 | 33 | |
| 23-Nov | | Indiana | L | 0 | 3 | |
| | 2-6-0 | | 96 | 106 | |
| | | | | | |
