| 1959 Clemson Football Schedule | | | | |
| 19-Sep | at | North Carolina | W | 20 | 18 | |
| 26-Sep | at | Virginia | W | 47 | 0 | |
| 3-Oct | at | Georgia Tech | L | 6 | 16 | |
| 10-Oct | | North Carolina State | W | 23 | 0 | |
| 22-Oct | at | South Carolina | W | 27 | 0 | |
| 31-Oct | at | Rice | W | 19 | 0 | |
| 7-Nov | | Duke | W | 6 | 0 | |
| 14-Nov | | Maryland | L | 25 | 28 | |
| 21-Nov | | Wake Forest | W | 33 | 31 | |
| 28-Nov | at | Furman | W | 56 | 3 | |
| 19-Dec | N | Texas Christian | W | 23 | 7 | Bluebonnet-Houston, TX |
| | 9-2-0 | | 285 | 103 | |
| | | | | | | |
| 1958 Clemson Football Schedule | | | | |
| 20-Sep | | Virginia | W | 20 | 15 | |
| 27-Sep | | North Carolina | W | 26 | 21 | |
| 4-Oct | at | Maryland | W | 8 | 0 | |
| 11-Oct | at | Vanderbilt | W | 12 | 7 | |
| 23-Oct | at | South Carolina | L | 6 | 26 | |
| 1-Nov | | Wake Forest | W | 14 | 12 | |
| 8-Nov | at | Georgia Tech | L | 0 | 13 | |
| 15-Nov | at | North Carolina State | W | 13 | 6 | |
| 22-Nov | | Boston College | W | 34 | 12 | |
| 29-Nov | | Furman | W | 36 | 19 | |
| 1-Jan | N | Louisiana State | L | 0 | 7 | Sugar-New Orleans, LA |
| | 8-3-0 | | 169 | 138 | |
| | | | | | | |
| 1957 Clemson Football Schedule | | | | |
| 21-Sep | | Presbyterian | W | 66 | 0 | |
| 28-Sep | at | North Carolina | L | 0 | 26 | |
| 5-Oct | | North Carolina State | L | 7 | 13 | |
| 12-Oct | at | Virginia | W | 20 | 6 | |
| 24-Oct | at | South Carolina | W | 13 | 0 | |
| 2-Nov | at | Rice | W | 20 | 7 | |
| 9-Nov | | Maryland | W | 26 | 7 | |
| 16-Nov | at | Duke | L | 6 | 7 | |
| 23-Nov | | Wake Forest | W | 13 | 6 | |
| 30-Nov | at | Furman | W | 45 | 6 | |
| | 7-3-0 | | 216 | 78 | |
| | | | | | | |
| 1956 Clemson Football Schedule | | | | |
| 22-Sep | | Presbyterian | W | 27 | 7 | |
| 29-Sep | at | Florida | T | 20 | 20 | |
| 6-Oct | at | North Carolina State | W | 13 | 7 | |
| 13-Oct | at | Wake Forest | W | 17 | 0 | |
| 25-Oct | at | South Carolina | W | 7 | 0 | |
| 3-Nov | | Virginia Tech | W | 21 | 6 | |
| 10-Nov | at | Maryland | T | 6 | 6 | |
| 16-Nov | at | Miami | L | 0 | 21 | |
| 24-Nov | | Virginia | W | 7 | 0 | |
| 1-Dec | | Furman | W | 28 | 7 | |
| 1-Jan | N | Colorado | L | 21 | 27 | Orange-Miami, FL |
| | 7-2-2 | | 167 | 101 | |
| | | | | | | |
| 1955 Clemson Football Schedule | | | | |
| 17-Sep | | Presbyterian | W | 33 | 0 | |
| 24-Sep | at | Virginia | W | 20 | 7 | |
| 1-Oct | | Georgia | W | 26 | 7 | |
| 8-Oct | at | Rice | L | 7 | 21 | |
| 20-Oct | at | South Carolina | W | 28 | 14 | |
| 29-Oct | | Wake Forest | W | 19 | 13 | |
| 5-Nov | N | Virginia Tech | W | 21 | 16 | Roanoke, VA |
| 12-Nov | | Maryland | L | 12 | 25 | |
| 19-Nov | N | Auburn | L | 0 | 21 | Mobile, AL |
| 26-Nov | at | Furman | W | 40 | 20 | |
| | 7-3-0 | | 206 | 144 | |
| | | | | | | |
| 1954 Clemson Football Schedule | | | | |
| 18-Sep | | Presbyterian | W | 33 | 0 | |
| 25-Sep | at | Georgia | L | 7 | 14 | |
| 2-Oct | | Virginia Tech | L | 7 | 18 | |
| 9-Oct | N | Florida | W | 14 | 7 | Jacksonville, FL |
| 21-Oct | at | South Carolina | L | 8 | 13 | |
| 30-Oct | N | Wake Forest | W | 32 | 20 | Charlotte, NC |
| 6-Nov | | Furman | W | 27 | 6 | |
| 13-Nov | at | Maryland | L | 0 | 16 | |
| 20-Nov | at | Auburn | L | 6 | 27 | |
| 27-Nov | | Citadel | W | 59 | 0 | |
| | 5-5-0 | | 193 | 121 | |
| | | | | | | |
| 1953 Clemson Football Schedule | | | | |
| 19-Sep | | Presbyterian | W | 33 | 7 | |
| 26-Sep | at | Boston College | T | 14 | 14 | |
| 3-Oct | | Maryland | L | 0 | 20 | |
| 9-Oct | at | Miami | L | 7 | 39 | |
| 22-Oct | at | South Carolina | L | 7 | 14 | |
| 31-Oct | | Wake Forest | W | 18 | 0 | |
| 7-Nov | at | Georgia Tech | L | 7 | 20 | |
| 14-Nov | at | Citadel | W | 34 | 13 | |
| 21-Nov | | Auburn | L | 19 | 45 | |
| | 3-5-1 | | 139 | 172 | |
| | | | | | | |
| 1952 Clemson Football Schedule | | | | |
| 20-Sep | | Presbyterian | W | 53 | 13 | |
| 27-Sep | | Villanova | L | 7 | 14 | |
| 4-Oct | at | Maryland | L | 0 | 28 | |
| 11-Oct | at | Florida | L | 13 | 54 | |
| 23-Oct | at | South Carolina | L | 0 | 6 | |
| 31-Oct | at | Boston College | W | 13 | 0 | |
| 8-Nov | N | Fordham | T | 12 | 12 | Randalls Island, NY |
| 15-Nov | at | Kentucky | L | 14 | 27 | |
| 22-Nov | at | Auburn | L | 0 | 3 | |
| | 2-6-1 | | 112 | 157 | |
| | | | | | | |
| 1951 Clemson Football Schedule | | | | |
| 22-Sep | | Presbyterian | W | 53 | 6 | |
| 29-Sep | at | Rice | W | 20 | 14 | |
| 6-Oct | at | North Carolina State | W | 6 | 0 | |
| 13-Oct | at | Pacific | L | 7 | 21 | |
| 25-Oct | at | South Carolina | L | 0 | 20 | |
| 3-Nov | | Wake Forest | W | 21 | 6 | |
| 10-Nov | | Boston College | W | 21 | 2 | |
| 17-Nov | at | Furman | W | 34 | 14 | |
| 24-Nov | | Auburn | W | 34 | 0 | |
| 1-Jan | N | Miami | L | 0 | 14 | Gator-Jacksonville, FL |
| | 7-3-0 | | 196 | 97 | |
| | | | | | | |
| 1950 Clemson Football Schedule | | | | |
| 23-Sep | | Presbyterian | W | 55 | 0 | |
| 30-Sep | at | Missouri | W | 34 | 0 | |
| 7-Oct | | North Carolina State | W | 27 | 0 | |
| 19-Oct | at | South Carolina | T | 14 | 14 | |
| 28-Oct | at | Wake Forest | W | 13 | 12 | |
| 4-Nov | | Duquesne | W | 53 | 20 | |
| 11-Nov | at | Boston College | W | 35 | 14 | |
| 18-Nov | | Furman | W | 57 | 2 | |
| 25-Nov | at | Auburn | W | 41 | 0 | |
| 1-Jan | N | Miami | W | 15 | 14 | Orange-Miami, FL |
| | 9-0-1 | | 344 | 76 | |
